![]() ![]() Restenosis rates after PTA vary from 6% to 60% at 1 year depending on the localization, type and length of the original lesion. However, its main limitation is an increased risk of late restenosis/reocclusion, which usually develops 3–12 months after PTA. ![]() Percutaneous transluminal balloon angioplasty (PTA) is a routine and widely accepted method for the treatment of peripheral arterial disease ( 1). Basic and applied research should continue to focus on enlargement of plaque ablation. The main drawback of laser angioplasty is that current laser catheters are not able to create a sufficiently wide channel in the occlusion, meaning that adjunctive balloon dilatation is still required. In comparison to conventional PTA, there are some advantages of laser angioplasty: easier passage through chronic and calcified occlusions and according to some studies, better short- and medium-term results regarding limb salvage and management of in-stent restenoses. Large clinical studies using laser angioplasty are critically assessed. We discuss the principles of lasers, physical properties of laser light, history of laser angioplasty and effects of laser radiation on tissues. Laser angioplasty is one method to remove atherosclerotic plaques. It is hypothesized that better long-term angioplasty results are observed if atherosclerotic plaques are removed rather than compressed and fractured. Restenosis arises from injury to the arterial wall including overstretching, compression and rupture of the atherosclerotic plaque during balloon inflation. However, its main limitation is late restenosis occurring at a 1-year rate of 6%–60%. ![]() Percutaneous transluminal angioplasty (PTA) is a routine procedure for the treatment of peripheral arterial disease. ![]()
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